Cargando…
Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions
Glomerular mesangial cells (MCs) hypertrophy is one of the earliest pathological abnormalities in diabetic nephropathy (DN), which correlates with eventual glomerulosclerosis. This study aimed to investigate the therapeutic role of miRNA in diabetic glomerular MCs hypertrophy and synthesis of extrac...
Autores principales: | Wang, Xiaoxia, Shen, E., Wang, Yanzhe, Li, Junhui, Cheng, Dongsheng, Chen, Yuqiang, Gui, Dingkun, Wang, Niansong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994004/ https://www.ncbi.nlm.nih.gov/pubmed/27549568 http://dx.doi.org/10.1038/srep31506 |
Ejemplares similares
-
Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Mellitus Patients with Moderate to Severe Renal Impairment: A Systematic Review and Meta-Analysis
por: Cheng, Dongsheng, et al.
Publicado: (2014) -
Increased Serum Uric Acid Level Is a Risk Factor for Left Ventricular Hypertrophy but Not Independent of eGFR in Patients with Type 2 Diabetic Kidney Disease
por: Zeng, Chuchu, et al.
Publicado: (2017) -
MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN
por: Yang, Ting-Song, et al.
Publicado: (2013) -
miR-26a and miR-214 down-regulate expression of the PTEN gene in chronic lymphocytic leukemia, but not PTEN mutation or promoter methylation
por: Zou, Zhi-Jian, et al.
Publicado: (2014) -
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy
por: Li, Yan, et al.
Publicado: (2021)