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SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment
Most tumors initially respond to cytotoxic treatments, but acquired resistance often follows. The tumor microenvironment (TME) is a major barrier to clinical success by compromising therapeutic efficacy, and pathological relevance of multiple soluble factors released by a therapeutically remodeled T...
Autores principales: | Sun, Y, Zhu, D, Chen, F, Qian, M, Wei, H, Chen, W, Xu, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994019/ https://www.ncbi.nlm.nih.gov/pubmed/26751775 http://dx.doi.org/10.1038/onc.2015.494 |
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