High throughput cytotoxicity screening of anti-HER2 immunotoxins conjugated with antibody fragments from phage-displayed synthetic antibody libraries

Immunotoxins are an important class of antibody-based therapeutics. The potency of the immunotoxins depends on the antibody fragments as the guiding modules targeting designated molecules on cell surfaces. Phage-displayed synthetic antibody scFv libraries provide abundant antibody fragment candidate...

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Detalles Bibliográficos
Autores principales: Hou, Shin-Chen, Chen, Hong-Sen, Lin, Hung-Wei, Chao, Wei-Ting, Chen, Yao-Sheng, Fu, Chi-Yu, Yu, Chung-Ming, Huang, Kai-Fa, Wang, Andrew H.-J., Yang, An-Suei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994030/
https://www.ncbi.nlm.nih.gov/pubmed/27550798
http://dx.doi.org/10.1038/srep31878

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