Human Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage

Reliable test systems to identify hepatotoxicity are essential to predict unexpected drug-related liver injury. Here we present a human ex-vivo liver model to investigate acetaminophen-induced liver injury. Human liver tissue was perfused over a 30 hour period with hourly sampling from the perfusate...

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Detalles Bibliográficos
Autores principales: Schreiter, Thomas, Sowa, Jan-Peter, Schlattjan, Martin, Treckmann, Jürgen, Paul, Andreas, Strucksberg, Karl-Heinz, Baba, Hideo A., Odenthal, Margarete, Gieseler, Robert K., Gerken, Guido, Arteel, Gavin E., Canbay, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994032/
https://www.ncbi.nlm.nih.gov/pubmed/27550092
http://dx.doi.org/10.1038/srep31916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994032/
https://www.ncbi.nlm.nih.gov/pubmed/27550092
http://dx.doi.org/10.1038/srep31916

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