Cognitive deficits caused by a disease-mutation in the α(3) Na(+)/K(+)-ATPase isoform

The Na(+)/K(+)-ATPases maintain Na(+) and K(+) electrochemical gradients across the plasma membrane, a prerequisite for electrical excitability and secondary transport in neurons. Autosomal dominant mutations in the human ATP1A3 gene encoding the neuron-specific Na(+)/K(+)-ATPase α(3) isoform cause...

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Detalles Bibliográficos
Autores principales: Holm, Thomas Hellesøe, Isaksen, Toke Jost, Glerup, Simon, Heuck, Anders, Bøttger, Pernille, Füchtbauer, Ernst-Martin, Nedergaard, Steen, Nyengaard, Jens Randel, Andreasen, Mogens, Nissen, Poul, Lykke-Hartmann, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994072/
https://www.ncbi.nlm.nih.gov/pubmed/27549929
http://dx.doi.org/10.1038/srep31972

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