Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

Skeletal muscle atrophy, referred to as sarcopenia, is often observed in chronic kidney disease (CKD) patients, especially in patients who are undergoing hemodialysis. The purpose of this study was to determine whether uremic toxins are involved in CKD-related skeletal muscle atrophy. Among six prot...

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Detalles Bibliográficos
Autores principales: Enoki, Yuki, Watanabe, Hiroshi, Arake, Riho, Sugimoto, Ryusei, Imafuku, Tadashi, Tominaga, Yuna, Ishima, Yu, Kotani, Shunsuke, Nakajima, Makoto, Tanaka, Motoko, Matsushita, Kazutaka, Fukagawa, Masafumi, Otagiri, Masaki, Maruyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994088/
https://www.ncbi.nlm.nih.gov/pubmed/27549031
http://dx.doi.org/10.1038/srep32084

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