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Genome-wide association study to identify potential genetic modifiers in a canine model for Duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) causes progressive muscle degeneration, cardiomyopathy and respiratory failure in approximately 1/5,000 boys. Golden Retriever muscular dystrophy (GRMD) resembles DMD both clinically and pathologically. Like DMD, GRMD exhibits remarkable phenotypic varia...

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Detalles Bibliográficos
Autores principales: Brinkmeyer-Langford, Candice, Balog-Alvarez, Cynthia, Cai, James J., Davis, Brian W., Kornegay, Joe N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994242/
https://www.ncbi.nlm.nih.gov/pubmed/27549615
http://dx.doi.org/10.1186/s12864-016-2948-z