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A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein

BACKGROUND: Alpha-synuclein (asyn) has been shown to play an important role in the neuropathology of Parkinson’s disease (PD). In the diseased brain, classic intraneuronal inclusions called Lewy bodies contain abnormal formations of asyn protein which is mostly phosphorylated at serine 129 (pS129 as...

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Detalles Bibliográficos
Autores principales:	Landeck, Natalie, Hall, Hélène, Ardah, Mustafa T., Majbour, Nour K., El-Agnaf, Omar M. A., Halliday, Glenda, Kirik, Deniz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994244/ https://www.ncbi.nlm.nih.gov/pubmed/27549140 http://dx.doi.org/10.1186/s13024-016-0125-0

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