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HIV-1 Tat protein vaccination in mice infected with Mycobacterium tuberculosis is safe, immunogenic and reduces bacterial lung pathology

BACKGROUND: The therapeutic HIV-1 Tat protein vaccine is in advanced clinical development. Tuberculosis, the main AIDS co-infection, is highly endemic in areas where AIDS prevention through vaccination is needed. However, safety and immunogenicity of Tat vaccination in the course of Mycobacterium tu...

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Detalles Bibliográficos
Autores principales:	Cafaro, Aurelio, Piccaro, Giovanni, Altavilla, Giuseppe, Gigantino, Vincenzo, Matarese, Giuseppe, Olivieri, Erika, Ferrantelli, Flavia, Ensoli, Barbara, Palma, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994248/ https://www.ncbi.nlm.nih.gov/pubmed/27549342 http://dx.doi.org/10.1186/s12879-016-1724-7

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