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A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein

BACKGROUND: CASKIN2 is a homolog of CASKIN1, a scaffolding protein that participates in a signaling network with CASK (calcium/calmodulin-dependent serine kinase). Despite a high level of homology between CASKIN2 and CASKIN1, CASKIN2 cannot bind CASK due to the absence of a CASK Interaction Domain a...

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Detalles Bibliográficos
Autores principales: Smirnova, Ekaterina, Kwan, Jamie J., Siu, Ryan, Gao, Xin, Zoidl, Georg, Demeler, Borries, Saridakis, Vivian, Donaldson, Logan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994250/
https://www.ncbi.nlm.nih.gov/pubmed/27549312
http://dx.doi.org/10.1186/s12964-016-0140-3