Should tissue structure suppress or amplify selection to minimize cancer risk?

BACKGROUND: It has been frequently argued that tissues evolved to suppress the accumulation of growth enhancing cancer inducing mutations. A prominent example is the hierarchical structure of tissues with high cell turnover, where a small number of tissue specific stem cells produces a large number...

Descripción completa

Detalles Bibliográficos
Autores principales: Hindersin, Laura, Werner, Benjamin, Dingli, David, Traulsen, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994303/
https://www.ncbi.nlm.nih.gov/pubmed/27549612
http://dx.doi.org/10.1186/s13062-016-0140-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994303/
https://www.ncbi.nlm.nih.gov/pubmed/27549612
http://dx.doi.org/10.1186/s13062-016-0140-7

Ejemplares similares