Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015

We observed multidrug resistance in 10 (91%) of 11 Shigella isolates from a diarrheal surveillance study in Cambodia. One isolate was resistant to fluoroquinolones and cephalosporins and showed decreased susceptibility to azithromycin. We found mutations in gyrA, parC, β-lactamase, and mphA genes. M...

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Autores principales: Poramathikul, Kamonporn, Bodhidatta, Ladaporn, Chiek, Sivhour, Oransathid, Wilawan, Ruekit, Sirigade, Nobthai, Panida, Lurchachaiwong, Woradee, Serichantalergs, Oralak, Lon, Chanthap, Swierczewski, Brett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994341/
https://www.ncbi.nlm.nih.gov/pubmed/27532684
http://dx.doi.org/10.3201/eid2209.152058
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author Poramathikul, Kamonporn
Bodhidatta, Ladaporn
Chiek, Sivhour
Oransathid, Wilawan
Ruekit, Sirigade
Nobthai, Panida
Lurchachaiwong, Woradee
Serichantalergs, Oralak
Lon, Chanthap
Swierczewski, Brett
author_facet Poramathikul, Kamonporn
Bodhidatta, Ladaporn
Chiek, Sivhour
Oransathid, Wilawan
Ruekit, Sirigade
Nobthai, Panida
Lurchachaiwong, Woradee
Serichantalergs, Oralak
Lon, Chanthap
Swierczewski, Brett
author_sort Poramathikul, Kamonporn
collection PubMed
description We observed multidrug resistance in 10 (91%) of 11 Shigella isolates from a diarrheal surveillance study in Cambodia. One isolate was resistant to fluoroquinolones and cephalosporins and showed decreased susceptibility to azithromycin. We found mutations in gyrA, parC, β-lactamase, and mphA genes. Multidrug resistance increases concern about shigellosis treatment options.
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spelling pubmed-49943412016-09-08 Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015 Poramathikul, Kamonporn Bodhidatta, Ladaporn Chiek, Sivhour Oransathid, Wilawan Ruekit, Sirigade Nobthai, Panida Lurchachaiwong, Woradee Serichantalergs, Oralak Lon, Chanthap Swierczewski, Brett Emerg Infect Dis Dispatch We observed multidrug resistance in 10 (91%) of 11 Shigella isolates from a diarrheal surveillance study in Cambodia. One isolate was resistant to fluoroquinolones and cephalosporins and showed decreased susceptibility to azithromycin. We found mutations in gyrA, parC, β-lactamase, and mphA genes. Multidrug resistance increases concern about shigellosis treatment options. Centers for Disease Control and Prevention 2016-09 /pmc/articles/PMC4994341/ /pubmed/27532684 http://dx.doi.org/10.3201/eid2209.152058 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Poramathikul, Kamonporn
Bodhidatta, Ladaporn
Chiek, Sivhour
Oransathid, Wilawan
Ruekit, Sirigade
Nobthai, Panida
Lurchachaiwong, Woradee
Serichantalergs, Oralak
Lon, Chanthap
Swierczewski, Brett
Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015
title Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015
title_full Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015
title_fullStr Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015
title_full_unstemmed Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015
title_short Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015
title_sort multidrug-resistant shigella infections in patients with diarrhea, cambodia, 2014–2015
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994341/
https://www.ncbi.nlm.nih.gov/pubmed/27532684
http://dx.doi.org/10.3201/eid2209.152058
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