Antileukemia Effect of Ciclopirox Olamine Is Mediated by Downregulation of Intracellular Ferritin and Inhibition β-Catenin-c-Myc Signaling Pathway in Glucocorticoid Resistant T-ALL Cell Lines

Ciclopirox olamine (CPX) is an antifungal drug that has been reported to have antitumor effects. In this study we investigated the antileukemia effects and the possible mechanisms of CPX on glucocorticoid (GC)-resistant T-cell acute lymphoblastic leukemia (T-ALL) cell lines. The results indicated th...

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Detalles Bibliográficos
Autores principales: Wu, Jianrong, Liu, Huajun, Zhang, Ge, Gu, Ling, Zhang, Yanle, Gao, Ju, Wei, Yuquan, Ma, Zhigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995032/
https://www.ncbi.nlm.nih.gov/pubmed/27551974
http://dx.doi.org/10.1371/journal.pone.0161509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995032/
https://www.ncbi.nlm.nih.gov/pubmed/27551974
http://dx.doi.org/10.1371/journal.pone.0161509

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