Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection

Major histocompatibility complex class II (MHC II) expression is tightly regulated, being subjected to cell type–specific mechanisms that closely control its levels at the cell surface. Ubiquitination by the E3 ubiquitin ligase MARCH 1 regulates MHC II expression in dendritic cells and B cells. In t...

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Detalles Bibliográficos
Autores principales: Liu, Haiyin, Jain, Reema, Guan, Jing, Vuong, Vivian, Ishido, Satoshi, La Gruta, Nicole L., Gray, Daniel H., Villadangos, Jose A., Mintern, Justine D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995085/
https://www.ncbi.nlm.nih.gov/pubmed/27503069
http://dx.doi.org/10.1084/jem.20160312

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