Interleukin-4 Expressed By Neoplastic Cells Provokes an Anti-Metastatic Myeloid Immune Response

OBJECTIVE: Interleukin-4 (IL-4) can induce macrophages to undergo alternative activation and polarize toward an M2-like or wound healing phenotype. Tumor associated macrophages (TAMs) are thought to assume M2-like properties, and it has been suggested they promote tumor growth and metastasis through...

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Detalles Bibliográficos
Autores principales: Zhang, Connie S., Kim, Hyeyeon, Mullins, Graeme, Tyryshkin, Kathrin, LeBrun, David P., Elliott, Bruce E., Greer, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995104/
https://www.ncbi.nlm.nih.gov/pubmed/27563494

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