Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists?

SUMMARY: The volume of the hippocampus is reduced in patients with schizophrenia, and this deficit tends to become more pronounced with chronicity. Newer antipsychotics may protect against the progressive reductions in hippocampal volume while preliminary data offer hope that specific antipsychotics...

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Detalles Bibliográficos
Autor principal: Frangou, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal College of Psychiatrists 2016
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995174/
https://www.ncbi.nlm.nih.gov/pubmed/27703789
http://dx.doi.org/10.1192/bjpo.bp.116.002857
Descripción
Sumario:SUMMARY: The volume of the hippocampus is reduced in patients with schizophrenia, and this deficit tends to become more pronounced with chronicity. Newer antipsychotics may protect against the progressive reductions in hippocampal volume while preliminary data offer hope that specific antipsychotics may act to reverse it. DECLARATION OF INTEREST: None. COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2016. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence.

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