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Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists?
SUMMARY: The volume of the hippocampus is reduced in patients with schizophrenia, and this deficit tends to become more pronounced with chronicity. Newer antipsychotics may protect against the progressive reductions in hippocampal volume while preliminary data offer hope that specific antipsychotics...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Royal College of Psychiatrists
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995174/ https://www.ncbi.nlm.nih.gov/pubmed/27703789 http://dx.doi.org/10.1192/bjpo.bp.116.002857 |
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author | Frangou, Sophia |
author_facet | Frangou, Sophia |
author_sort | Frangou, Sophia |
collection | PubMed |
description | SUMMARY: The volume of the hippocampus is reduced in patients with schizophrenia, and this deficit tends to become more pronounced with chronicity. Newer antipsychotics may protect against the progressive reductions in hippocampal volume while preliminary data offer hope that specific antipsychotics may act to reverse it. DECLARATION OF INTEREST: None. COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2016. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence. |
format | Online Article Text |
id | pubmed-4995174 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Royal College of Psychiatrists |
record_format | MEDLINE/PubMed |
spelling | pubmed-49951742016-10-04 Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists? Frangou, Sophia BJPsych Open Editorial SUMMARY: The volume of the hippocampus is reduced in patients with schizophrenia, and this deficit tends to become more pronounced with chronicity. Newer antipsychotics may protect against the progressive reductions in hippocampal volume while preliminary data offer hope that specific antipsychotics may act to reverse it. DECLARATION OF INTEREST: None. COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2016. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence. The Royal College of Psychiatrists 2016-07-12 /pmc/articles/PMC4995174/ /pubmed/27703789 http://dx.doi.org/10.1192/bjpo.bp.116.002857 Text en © 2016 The Royal College of Psychiatrists http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Editorial Frangou, Sophia Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists? |
title | Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists? |
title_full | Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists? |
title_fullStr | Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists? |
title_full_unstemmed | Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists? |
title_short | Bulking up the hippocampus in schizophrenia: a role for 5-HT(1A) agonists? |
title_sort | bulking up the hippocampus in schizophrenia: a role for 5-ht(1a) agonists? |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995174/ https://www.ncbi.nlm.nih.gov/pubmed/27703789 http://dx.doi.org/10.1192/bjpo.bp.116.002857 |
work_keys_str_mv | AT frangousophia bulkingupthehippocampusinschizophreniaarolefor5ht1aagonists |