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Effector T cell subclasses associate with tumor burden in neurofibromatosis type 1 patients

Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome caused by mutations of the NF1 gene and resulting dysregulation of the Ras-pathway. In addition to peripheral nerve tumors, affected tissues include the musculoskeletal and cardiovascular system. The immune system has recently been sugges...

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Detalles Bibliográficos
Autores principales: Farschtschi, Said, Park, Su-Jin, Sawitzki, Birgit, Oh, Su-Jun, Kluwe, Lan, Mautner, Victor F., Kurtz, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995232/
https://www.ncbi.nlm.nih.gov/pubmed/27448806
http://dx.doi.org/10.1007/s00262-016-1871-0