Reduced molecular size and altered disaccharide composition of cerebral chondroitin sulfate upon Alzheimer’s pathogenesis in mice

Alzheimer’s disease (AD) is a progressive disorder leading to cognitive impairment and neuronal loss. Cerebral extracellular accumulation and deposition of amyloid ß plaques is a pathological hallmark of AD. Chondroitin sulfate (CS) is an extracellular component abundant in the brain. CS is a sulfat...

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Detalles Bibliográficos
Autores principales: Zhang, Zui, Ohtake-Niimi, Shiori, Kadomatsu, Kenji, Uchimura, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995275/
https://www.ncbi.nlm.nih.gov/pubmed/27578913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995275/
https://www.ncbi.nlm.nih.gov/pubmed/27578913

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