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TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21

TGF-β1, upregulated in keloid tissue, promotes the proliferation, collagen formation and differentiation of dermal fibroblasts. miR-21 is one of microRNAs first found in human genome. The aim of our study is to explore the mechanisms of miR-21 in TGF-β1-induced scar fibroblasts proliferation and tra...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Li, Yue, Li, Ning, Teng, Wen, Wang, Min, Zhang, Yingbo, Xiao, Zhibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995376/
https://www.ncbi.nlm.nih.gov/pubmed/27554193
http://dx.doi.org/10.1038/srep32231