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Oestradiol synthesized by female neurons generates sex differences in neuritogenesis

Testosterone produced by the foetal testis is converted by male neurons to oestradiol, which masculinizes neuronal morphology. Female neurons are known to synthesize oestradiol in absence of exogenous testosterone. However, the role of neuronal oestradiol on the differentiation of foetal female neur...

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Detalles Bibliográficos
Autores principales: Ruiz-Palmero, Isabel, Ortiz-Rodriguez, Ana, Melcangi, Roberto Cosimo, Caruso, Donatella, Garcia-Segura, Luis M., Rune, Gabriele M., Arevalo, Maria-Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995407/
https://www.ncbi.nlm.nih.gov/pubmed/27553191
http://dx.doi.org/10.1038/srep31891