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Oestradiol synthesized by female neurons generates sex differences in neuritogenesis
Testosterone produced by the foetal testis is converted by male neurons to oestradiol, which masculinizes neuronal morphology. Female neurons are known to synthesize oestradiol in absence of exogenous testosterone. However, the role of neuronal oestradiol on the differentiation of foetal female neur...
Autores principales: | Ruiz-Palmero, Isabel, Ortiz-Rodriguez, Ana, Melcangi, Roberto Cosimo, Caruso, Donatella, Garcia-Segura, Luis M., Rune, Gabriele M., Arevalo, Maria-Angeles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995407/ https://www.ncbi.nlm.nih.gov/pubmed/27553191 http://dx.doi.org/10.1038/srep31891 |
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