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PAFR activation of NF-κB p65 or p105 precursor dictates pro- and anti-inflammatory responses during TLR activation in murine macrophages

Platelet-activating factor receptor (PAFR) is a G protein-coupled receptor (GPCR) implicated in many diseases. Toll-like receptors (TLRs) play a critical role in shaping innate and adaptive immune responses. In this study, we investigated whether PAFR signaling changes the macrophages responsiveness...

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Detalles Bibliográficos
Autores principales:	Ishizuka, Edson K., Filgueiras, Luciano Ribeiro, Rios, Francisco J., Serezani, Carlos H., Jancar, Sonia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995467/ https://www.ncbi.nlm.nih.gov/pubmed/27554194 http://dx.doi.org/10.1038/srep32092

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