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Staphylokinase has distinct modes of interaction with antimicrobial peptides, modulating its plasminogen-activation properties
Staphylokinase (Sak) is a plasminogen activator protein that is secreted by many Staphylococcus aureus strains. Sak also offers protection by binding and inhibiting specific antimicrobial peptides (AMPs). Here, we evaluate Sak as a more general interaction partner for AMPs. Studies with melittin, mC...
Autores principales: | Nguyen, Leonard T., Vogel, Hans J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995489/ https://www.ncbi.nlm.nih.gov/pubmed/27554435 http://dx.doi.org/10.1038/srep31817 |
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