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Polygonatum sibiricum polysaccharide inhibits osteoporosis by promoting osteoblast formation and blocking osteoclastogenesis through Wnt/β-catenin signalling pathway
Bone homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts. Osteoporosis occurs when osteoclast activity surpasses osteoblast activity. Our previous studies showed the plant-derived natural polysaccharide (Polygonatum sibiricum polysaccharide...
Autores principales: | Du, Li, Nong, Meng-Ni, Zhao, Jin-Min, Peng, Xiao-Ming, Zong, Shao-Hui, Zeng, Gao-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995504/ https://www.ncbi.nlm.nih.gov/pubmed/27554324 http://dx.doi.org/10.1038/srep32261 |
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