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Polygonatum sibiricum polysaccharide inhibits osteoporosis by promoting osteoblast formation and blocking osteoclastogenesis through Wnt/β-catenin signalling pathway

Bone homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts. Osteoporosis occurs when osteoclast activity surpasses osteoblast activity. Our previous studies showed the plant-derived natural polysaccharide (Polygonatum sibiricum polysaccharide...

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Detalles Bibliográficos
Autores principales: Du, Li, Nong, Meng-Ni, Zhao, Jin-Min, Peng, Xiao-Ming, Zong, Shao-Hui, Zeng, Gao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995504/
https://www.ncbi.nlm.nih.gov/pubmed/27554324
http://dx.doi.org/10.1038/srep32261

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