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Cancer network activity associated with therapeutic response and synergism

BACKGROUND: Cancer patients often show no or only modest benefit from a given therapy. This major problem in oncology is generally attributed to the lack of specific predictive biomarkers, yet a global measure of cancer cell activity may support a comprehensive mechanistic understanding of therapy e...

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Detalles Bibliográficos
Autores principales: Serra-Musach, Jordi, Mateo, Francesca, Capdevila-Busquets, Eva, de Garibay, Gorka Ruiz, Zhang, Xiaohu, Guha, Raj, Thomas, Craig J., Grueso, Judit, Villanueva, Alberto, Jaeger, Samira, Heyn, Holger, Vizoso, Miguel, Pérez, Hector, Cordero, Alex, Gonzalez-Suarez, Eva, Esteller, Manel, Moreno-Bueno, Gema, Tjärnberg, Andreas, Lázaro, Conxi, Serra, Violeta, Arribas, Joaquín, Benson, Mikael, Gustafsson, Mika, Ferrer, Marc, Aloy, Patrick, Pujana, Miquel Àngel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995628/
https://www.ncbi.nlm.nih.gov/pubmed/27553366
http://dx.doi.org/10.1186/s13073-016-0340-x