High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients

BACKGROUND: Women harboring BRCA1/2 germline mutations have high lifetime risk of developing breast/ovarian cancer. The recommendation to pursue BRCA1/2 testing is based on patient’s family history of breast/ovarian cancer, age of disease-onset and/or pathologic parameters of breast tumors. Here, we...

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Detalles Bibliográficos
Autores principales: Rashid, Muhammad Usman, Muhammad, Noor, Bajwa, Seerat, Faisal, Saima, Tahseen, Muhammad, Bermejo, Justo Lorenzo, Amin, Asim, Loya, Asif, Hamann, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995655/
https://www.ncbi.nlm.nih.gov/pubmed/27553291
http://dx.doi.org/10.1186/s12885-016-2698-y

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