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Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study)

BACKGROUND: Most estimates of postpartum hemorrhage (PPH) are calculated from studies that use administrative or medical birth databases, and only a few from prospective observational studies. Our principal objective was to estimate the incidence of PPH according to their severity (mild or severe) i...

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Autores principales: Vendittelli, Françoise, Barasinski, Chloé, Pereira, Bruno, Lémery, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995746/
https://www.ncbi.nlm.nih.gov/pubmed/27552986
http://dx.doi.org/10.1186/s12884-016-1008-7
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author Vendittelli, Françoise
Barasinski, Chloé
Pereira, Bruno
Lémery, Didier
author_facet Vendittelli, Françoise
Barasinski, Chloé
Pereira, Bruno
Lémery, Didier
author_sort Vendittelli, Françoise
collection PubMed
description BACKGROUND: Most estimates of postpartum hemorrhage (PPH) are calculated from studies that use administrative or medical birth databases, and only a few from prospective observational studies. Our principal objective was to estimate the incidence of PPH according to their severity (mild or severe) in vaginal deliveries (>500 mL, ≥1000 mL) and cesareans (>1000 mL and ≥1500 mL). The secondary objectives were to describe the incidence of PPH according to maternity unit characteristics, causes, and types of PPH management. METHODS: This prospective observational study took place in French maternity wards. Women who gave birth at a term ≥ 22 weeks were eligible for the study. 182 maternity units participated in a study with prospective data collection from 1 February, 2011, to 31 July, 2011. The main outcome measure was PPH incidence. RESULTS: PPH incidence after vaginal delivery was 3.36 % [95 % CI: 3.25–3.47 %] and after cesareans 2.83 % [95 % CI: 2.63–3.04 %]. The incidence of severe PPH after vaginal delivery was 1.11 % [95 % CI: 1.05–1.18 %] and after cesareans 1.00 % [95 % CI: 0.88–1.13 %]. This incidence rate varied according to maternity unit characteristics. The principal cause of PPH for both modes of delivery was uterine atony (57.7 % for vaginal births and 66.3 % for cesareans). Vascular embolization was more frequent among women with cesareans (10.0 vs. 2.9 %), who also required transfusions more often (44.4 vs 12.7 %). CONCLUSIONS: The incidence of PPH was lower than the rate expected from the literature. Effective treatment of uterine atony and optimizing the identification of blood loss remain important priorities. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12884-016-1008-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-49957462016-08-25 Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study) Vendittelli, Françoise Barasinski, Chloé Pereira, Bruno Lémery, Didier BMC Pregnancy Childbirth Research Article BACKGROUND: Most estimates of postpartum hemorrhage (PPH) are calculated from studies that use administrative or medical birth databases, and only a few from prospective observational studies. Our principal objective was to estimate the incidence of PPH according to their severity (mild or severe) in vaginal deliveries (>500 mL, ≥1000 mL) and cesareans (>1000 mL and ≥1500 mL). The secondary objectives were to describe the incidence of PPH according to maternity unit characteristics, causes, and types of PPH management. METHODS: This prospective observational study took place in French maternity wards. Women who gave birth at a term ≥ 22 weeks were eligible for the study. 182 maternity units participated in a study with prospective data collection from 1 February, 2011, to 31 July, 2011. The main outcome measure was PPH incidence. RESULTS: PPH incidence after vaginal delivery was 3.36 % [95 % CI: 3.25–3.47 %] and after cesareans 2.83 % [95 % CI: 2.63–3.04 %]. The incidence of severe PPH after vaginal delivery was 1.11 % [95 % CI: 1.05–1.18 %] and after cesareans 1.00 % [95 % CI: 0.88–1.13 %]. This incidence rate varied according to maternity unit characteristics. The principal cause of PPH for both modes of delivery was uterine atony (57.7 % for vaginal births and 66.3 % for cesareans). Vascular embolization was more frequent among women with cesareans (10.0 vs. 2.9 %), who also required transfusions more often (44.4 vs 12.7 %). CONCLUSIONS: The incidence of PPH was lower than the rate expected from the literature. Effective treatment of uterine atony and optimizing the identification of blood loss remain important priorities. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12884-016-1008-7) contains supplementary material, which is available to authorized users. BioMed Central 2016-08-24 /pmc/articles/PMC4995746/ /pubmed/27552986 http://dx.doi.org/10.1186/s12884-016-1008-7 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Vendittelli, Françoise
Barasinski, Chloé
Pereira, Bruno
Lémery, Didier
Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study)
title Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study)
title_full Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study)
title_fullStr Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study)
title_full_unstemmed Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study)
title_short Incidence of immediate postpartum hemorrhages in French maternity units: a prospective observational study (HERA study)
title_sort incidence of immediate postpartum hemorrhages in french maternity units: a prospective observational study (hera study)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995746/
https://www.ncbi.nlm.nih.gov/pubmed/27552986
http://dx.doi.org/10.1186/s12884-016-1008-7
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