Cargando…

Comparative effectiveness of levetiracetam, valproate and carbamazepine among elderly patients with newly diagnosed epilepsy: subgroup analysis of the randomized, unblinded KOMET study

BACKGROUND: Few clinical trials have evaluated the efficacy and tolerability of antiepileptic drugs (AEDs) as initial monotherapy for elderly patients. METHODS: This post-hoc subgroup analysis of data from an unblinded, randomized, 52-week superiority study (KOMET) compared the effectiveness of leve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pohlmann-Eden, Bernd, Marson, Anthony G., Noack-Rink, Matthias, Ramirez, Francisco, Tofighy, Azita, Werhahn, Konrad J., Wild, Imane, Trinka, Eugen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995751/ https://www.ncbi.nlm.nih.gov/pubmed/27552848 http://dx.doi.org/10.1186/s12883-016-0663-7

Ejemplares similares

Neurocognition after prenatal levetiracetam, lamotrigine, carbamazepine or valproate exposure
por: Huber-Mollema, Yfke, et al.
Publicado: (2020)

Behavioral problems in children of mothers with epilepsy prenatally exposed to valproate, carbamazepine, lamotrigine, or levetiracetam monotherapy
por: Huber‐Mollema, Yfke, et al.
Publicado: (2019)

Assessment of the biomarkers of hepatotoxicity following carbamazepine, levetiracetam, and carbamazepine-levetiracetam adjunctive treatment in male Wistar rats
por: Osuntokun, Opeyemi Samson, et al.
Publicado: (2021)

Efficacy and Safety of Levetiracetam and Carbamazepine as Monotherapy in Partial Seizures
por: Suresh, Swaroop Hassan, et al.
Publicado: (2015)

Levetiracetam, lamotrigine and carbamazepine: which monotherapy during pregnancy?
por: Mari, Luisa, et al.
Publicado: (2021)

Levetiracetam/sodium valproate: Lack of efficacy: case report
Publicado: (2022)

Lacosamide/levetiracetam/valproate: Lack of efficacy: case report
Publicado: (2022)

Cognitive dysfunction in Nigerian women with epilepsy on carbamazepine and levetiracetam monotherapy
por: Ogunjimi, Luqman, et al.
Publicado: (2021)

Effects of Levetiracetam Compared to Valproate on Cognitive Functions of Patients with Epilepsy
por: El Sabaa, Ramy M, et al.
Publicado: (2020)

Infrequent Monitoring of the Effects of Valproate and Carbamazepine Therapy in Patients With Epilepsy in Nigeria
por: Eshiet, Unyime Israel, et al.
Publicado: (2020)

Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters
por: Iannaccone, Teresa, et al.
Publicado: (2021)

For the love of all that is holy, stop prescribing sodium valproate and carbamazepine together
por: Jawaid, Wajid
Publicado: (2023)

Efficacy and Safety of Intravenous Valproate for Status Epilepticus: A Systematic Review
por: Trinka, Eugen, et al.
Publicado: (2014)

Neuropsychological effects of antiepileptic drugs (carbamazepine versus valproate) in adult males with epilepsy
por: Shehata, Ghaydaa A, et al.
Publicado: (2009)

Study of Visual Function in Adult Epileptic Patients on Sodium Valproate or Carbamazepine Monotherapy
por: Matthew, Tong Jong Haw, et al.
Publicado: (2019)

Differential effects of carbamazepine and levetiracetam monotherapy on reproductive endocrine function in Nigerian women with epilepsy
por: Ogunjimi, Luqman, et al.
Publicado: (2023)

Comparison of Levetiracetam and sodium Valproate in migraine prophylaxis: A randomized placebo-controlled study
por: Sadeghian, Homa, et al.
Publicado: (2015)

Effect of lamotrigine, levetiracetam & topiramate on neurobehavioural parameters & oxidative stress in comparison with valproate in rats
por: Sarangi, Sudhir Chandra, et al.
Publicado: (2016)

Comparative Efficacy of IV Phenytoin, IV Valproate, and IV Levetiracetam in Childhood Status Epilepticus
por: Nazir, Mudasir, et al.
Publicado: (2020)

Analysis of the Clinical Effects of Sodium Valproate and Levetiracetam in the Treatment of Women with Epilepsy during Pregnancy
por: Lv, Haiqiong, et al.
Publicado: (2021)

A description of sodium valproate, lamotrigine and levetiracetam consumption in the Western Cape public sector
por: Keuler, Nicole, et al.
Publicado: (2022)

The Investigation of Insulin Resistance in Two Groups of Epileptic Patients Treated with Sodium Valproate and Carbamazepine
por: Najafi, Mohammad Reza, et al.
Publicado: (2017)

Effects of Carbamazepine and Valproate on Serum Aspartate Aminotransferase, Alanine Aminotransferase and Gamma - Glutamyltransferase in Children
por: Hadzagic-Catibusic, Feriha, et al.
Publicado: (2017)

Comparison of myocardial perfusion between the users of two antiepileptic medications: valproate vs. carbamazepine
por: Peymani, Zeinab, et al.
Publicado: (2023)

Natural unblinding of BCG vaccination trials
por: Szigeti, Reka, et al.
Publicado: (2021)

Levetiracetam (levebel) Versus Carbamazepine Monotherapy for Focal Epilepsy in Children: A randomized clinical trial
por: AKHONDIAN, Javad, et al.
Publicado: (2020)

The Impact of Levetiracetam and Valproate on Platelet Functions—A Double-Blind, Placebo-Controlled Crossover Study
por: Olaizola, Itziar, et al.
Publicado: (2023)

Retracted: Analysis of the Clinical Effects of Sodium Valproate and Levetiracetam in the Treatment of Women with Epilepsy during Pregnancy
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Levetiracetam and non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation and epilepsy: a reasonable combination
por: von Oertzen, Tim J, et al.
Publicado: (2019)

Reply: Unblinding in the lecanemab trial in Alzheimer’s disease
por: Hardy, John, et al.
Publicado: (2023)

Serum Total Antioxidant Capacity of Epileptic Children before and after Monotherapy with Sodium Valproate, Carbamazepine, and Phenobarbital
por: ASHRAFI, Mahmoud Reza, et al.
Publicado: (2018)

The effect of sodium valproate on chronic daily headache and its subgroups
por: Yurekli, Vedat Ali, et al.
Publicado: (2008)

The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
por: Marson, Anthony, et al.
Publicado: (2021)

Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy
por: Farzi, Mohammad Amin
Publicado: (2022)

Efficacy and safety of levetiracetam versus valproate in patients with established status epilepticus: A systematic review and meta-analysis
por: Wang, Shixin, et al.
Publicado: (2023)

Role of cinnarizine and nifedipine on anticonvulsant effect of sodium valproate and carbamazepine in maximal electroshock and pentylenetetrazole model of seizures in mice
por: Brahmane, Ranjana I., et al.
Publicado: (2010)

A Comparative Study on the Efficacy of Levetiracetam and Carbamazepine in the Treatment of Rolandic Seizures in Children: An Open-Label Randomized Controlled Trial
por: Ahadi, Parisa, et al.
Publicado: (2020)

Sodium valproate combined with levetiracetam in pediatric epilepsy and its influence on NSE, IL-6, hs-CRP and electroencephalogram improvement
por: Liu, Zhaoyang, et al.
Publicado: (2020)

Efficacy of levetiracetam combined with sodium valproate on pediatric epilepsy and its effect on serum miR-106b in children
por: Zhao, Jiaqiang, et al.
Publicado: (2019)

Comparison of the Therapeutic Effects of Sodium Valproate and Levetiracetam on Pediatric Epilepsy and the Effects of Nerve Growth Factor and γ-Aminobutyric Acid
por: CHEN, Min, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cng2e58f3hgv07tl38uduabaql