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Destaining of Diff-Quik stained cytologic smears is not necessary for the detection of anaplastic lymphoma kinase gene rearrangement in lung adenocarcinoma by fluorescence in situ hybridization

BACKGROUND: Anaplastic lymphoma kinase (ALK) gene rearrangement analysis by fluorescence in situ hybridization (FISH) is one of the standard molecular tests for targeted therapy of lung adenocarcinoma. However, insufficient cell block cellularity may impede molecular testing. A recent study showed t...

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Detalles Bibliográficos
Autores principales: Xu, Weisheng, Khurana, Kamal K, Tull, Jamie, Maciak, Charlene, Zhang, Shengle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995874/
https://www.ncbi.nlm.nih.gov/pubmed/27756989
http://dx.doi.org/10.4103/0970-9371.188061