Cargando…
The Role of Constitutional Copy Number Variants in Breast Cancer
Constitutional copy number variants (CNVs) include inherited and de novo deviations from a diploid state at a defined genomic region. These variants contribute significantly to genetic variation and disease in humans, including breast cancer susceptibility. Identification of genetic risk factors for...
Autores principales: | Walker, Logan C., Wiggins, George A.R., Pearson, John F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996380/ https://www.ncbi.nlm.nih.gov/pubmed/27600231 http://dx.doi.org/10.3390/microarrays4030407 |
Ejemplares similares
-
Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry
por: Walker, Logan C., et al.
Publicado: (2017) -
Germline copy number variants are not associated with globally acquired copy number changes in familial breast tumours
por: Walker, Logan C., et al.
Publicado: (2012) -
Copy number variations and constitutional chromothripsis (Review)
por: Brás, Aldina, et al.
Publicado: (2020) -
Impact of constitutional copy number variants on biological pathway evolution
por: Poptsova, Maria, et al.
Publicado: (2013) -
Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers
por: Walker, Logan C, et al.
Publicado: (2017)