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3D Cultivation Techniques for Primary Human Hepatocytes

One of the main challenges in drug development is the prediction of in vivo toxicity based on in vitro data. The standard cultivation system for primary human hepatocytes is based on monolayer cultures, even if it is known that these conditions result in a loss of hepatocyte morphology and of liver-...

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Detalles Bibliográficos
Autores principales:	Bachmann, Anastasia, Moll, Matthias, Gottwald, Eric, Nies, Cordula, Zantl, Roman, Wagner, Helga, Burkhardt, Britta, Sánchez, Juan J. Martínez, Ladurner, Ruth, Thasler, Wolfgang, Damm, Georg, Nussler, Andreas K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996383/ https://www.ncbi.nlm.nih.gov/pubmed/27600213 http://dx.doi.org/10.3390/microarrays4010064

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