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Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection

The genetic markers associated with economic traits have been widely explored for animal breeding. Among these markers, single-nucleotide polymorphism (SNPs) are gradually becoming a prevalent and effective evaluation tool. Since SNPs only focus on the genetic sequences of interest, it thereby reduc...

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Autores principales: Huang, Chao-Wei, Lin, Yu-Tsung, Ding, Shih-Torng, Lo, Ling-Ling, Wang, Pei-Hwa, Lin, En-Chung, Liu, Fang-Wei, Lu, Yen-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996412/
https://www.ncbi.nlm.nih.gov/pubmed/27600241
http://dx.doi.org/10.3390/microarrays4040570
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author Huang, Chao-Wei
Lin, Yu-Tsung
Ding, Shih-Torng
Lo, Ling-Ling
Wang, Pei-Hwa
Lin, En-Chung
Liu, Fang-Wei
Lu, Yen-Wen
author_facet Huang, Chao-Wei
Lin, Yu-Tsung
Ding, Shih-Torng
Lo, Ling-Ling
Wang, Pei-Hwa
Lin, En-Chung
Liu, Fang-Wei
Lu, Yen-Wen
author_sort Huang, Chao-Wei
collection PubMed
description The genetic markers associated with economic traits have been widely explored for animal breeding. Among these markers, single-nucleotide polymorphism (SNPs) are gradually becoming a prevalent and effective evaluation tool. Since SNPs only focus on the genetic sequences of interest, it thereby reduces the evaluation time and cost. Compared to traditional approaches, SNP genotyping techniques incorporate informative genetic background, improve the breeding prediction accuracy and acquiesce breeding quality on the farm. This article therefore reviews the typical procedures of animal breeding using SNPs and the current status of related techniques. The associated SNP information and genotyping techniques, including microarray and Lab-on-a-Chip based platforms, along with their potential are highlighted. Examples in pig and poultry with different SNP loci linked to high economic trait values are given. The recommendations for utilizing SNP genotyping in nimal breeding are summarized.
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spelling pubmed-49964122016-09-06 Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection Huang, Chao-Wei Lin, Yu-Tsung Ding, Shih-Torng Lo, Ling-Ling Wang, Pei-Hwa Lin, En-Chung Liu, Fang-Wei Lu, Yen-Wen Microarrays (Basel) Review The genetic markers associated with economic traits have been widely explored for animal breeding. Among these markers, single-nucleotide polymorphism (SNPs) are gradually becoming a prevalent and effective evaluation tool. Since SNPs only focus on the genetic sequences of interest, it thereby reduces the evaluation time and cost. Compared to traditional approaches, SNP genotyping techniques incorporate informative genetic background, improve the breeding prediction accuracy and acquiesce breeding quality on the farm. This article therefore reviews the typical procedures of animal breeding using SNPs and the current status of related techniques. The associated SNP information and genotyping techniques, including microarray and Lab-on-a-Chip based platforms, along with their potential are highlighted. Examples in pig and poultry with different SNP loci linked to high economic trait values are given. The recommendations for utilizing SNP genotyping in nimal breeding are summarized. MDPI 2015-11-16 /pmc/articles/PMC4996412/ /pubmed/27600241 http://dx.doi.org/10.3390/microarrays4040570 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Huang, Chao-Wei
Lin, Yu-Tsung
Ding, Shih-Torng
Lo, Ling-Ling
Wang, Pei-Hwa
Lin, En-Chung
Liu, Fang-Wei
Lu, Yen-Wen
Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection
title Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection
title_full Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection
title_fullStr Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection
title_full_unstemmed Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection
title_short Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection
title_sort efficient snp discovery by combining microarray and lab-on-a-chip data for animal breeding and selection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996412/
https://www.ncbi.nlm.nih.gov/pubmed/27600241
http://dx.doi.org/10.3390/microarrays4040570
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