p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification

E-cadherin-mediated cell-cell adhesion is critical for naive pluripotency of cultured mouse embryonic stem cells (mESCs). E-cadherin-depleted mESC fail to downregulate their pluripotency program and are unable to initiate lineage commitment. To further explore the roles of cell adhesion molecules du...

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Detalles Bibliográficos
Autores principales: Pieters, Tim, Goossens, Steven, Haenebalcke, Lieven, Andries, Vanessa, Stryjewska, Agata, De Rycke, Riet, Lemeire, Kelly, Hochepied, Tino, Huylebroeck, Danny, Berx, Geert, Stemmler, Marc P., Wirth, Dagmar, Haigh, Jody J., van Hengel, Jolanda, van Roy, Frans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996431/
https://www.ncbi.nlm.nih.gov/pubmed/27556156
http://dx.doi.org/10.1371/journal.pgen.1006243

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