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Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix—A Comparative Analysis of Bioartificial Liver Microenvironments

Induced pluripotent stem cells (iPSCs) are new diagnostic and potentially therapeutic tools to model disease and assess the toxicity of pharmaceutical medications. A common limitation of cell lineages derived from iPSCs is a blunted phenotype compared with fully developed, endogenous cells. We exami...

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Detalles Bibliográficos
Autores principales:	Wang, Bo, Jakus, Adam E., Baptista, Pedro M., Soker, Shay, Soto-Gutierrez, Alejandro, Abecassis, Michael M., Shah, Ramille N., Wertheim, Jason A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AlphaMed Press 2016
Materias:	Tissue Engineering and Regenerative Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996436/ https://www.ncbi.nlm.nih.gov/pubmed/27421950 http://dx.doi.org/10.5966/sctm.2015-0235

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