Embryonic Ethanol Exposure Dysregulates BMP and Notch Signaling, Leading to Persistent Atrio-Ventricular Valve Defects in Zebrafish

Fetal alcohol spectrum disorder (FASD), birth defects associated with ethanol exposure in utero, includes a wide spectrum of congenital heart defects (CHDs), the most prevalent of which are septal and conotruncal defects. Zebrafish FASD model was used to dissect the mechanisms underlying FASD-associ...

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Detalles Bibliográficos
Autores principales: Sarmah, Swapnalee, Muralidharan, Pooja, Marrs, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996461/
https://www.ncbi.nlm.nih.gov/pubmed/27556898
http://dx.doi.org/10.1371/journal.pone.0161205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996461/
https://www.ncbi.nlm.nih.gov/pubmed/27556898
http://dx.doi.org/10.1371/journal.pone.0161205

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