Cargando…

Biophysical and Pharmacological Characterization of Nav1.9 Voltage Dependent Sodium Channels Stably Expressed in HEK-293 Cells

The voltage dependent sodium channel Nav1.9, is expressed preferentially in peripheral sensory neurons and has been linked to human genetic pain disorders, which makes it target of interest for the development of new pain therapeutics. However, characterization of Nav1.9 pharmacology has been limite...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Zhixin, Santos, Sonia, Padilla, Karen, Printzenhoff, David, Castle, Neil A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996523/ https://www.ncbi.nlm.nih.gov/pubmed/27556810 http://dx.doi.org/10.1371/journal.pone.0161450

Ejemplares similares

Cholesterol Down-Regulates BK Channels Stably Expressed in HEK 293 Cells
por: Wu, Wei, et al.
Publicado: (2013)

Effects of equol on multiple K(+) channels stably expressed in HEK 293 cells
por: Deng, Xiu-Ling, et al.
Publicado: (2017)

Characterization of bovine interleukin-2 stably expressed in HEK-293 cells
por: MITOMA, Shuya, et al.
Publicado: (2020)

Supramolecular clustering of the cardiac sodium channel Nav1.5 in HEK293F cells, with and without the auxiliary β3‐subunit
por: Salvage, Samantha C., et al.
Publicado: (2020)

A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line
por: Zhou, Xi, et al.
Publicado: (2018)

Immunogenicity and Antigenicity of the Ectodomain of Rabies Virus Glycoprotein Stably Expressed in HEK293T Cells
por: Li, Qingqing, et al.
Publicado: (2023)

The Natural Flavone Acacetin Blocks Small Conductance Ca(2+)-Activated K(+) Channels Stably Expressed in HEK 293 Cells
por: Chen, Kui-Hao, et al.
Publicado: (2017)

Voltage-Gated Sodium Channels: Biophysics, Pharmacology, and Related Channelopathies
por: Savio-Galimberti, Eleonora, et al.
Publicado: (2012)

The expression of endogenous voltage‐gated potassium channels in HEK293 cells is affected by culture conditions
por: Ponce, Arturo, et al.
Publicado: (2018)

Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3
por: Ghovanloo, Mohammad-Reza, et al.
Publicado: (2018)

Functional Expression of Rat Na(v)1.6 Voltage-Gated Sodium Channels in HEK293 Cells: Modulation by the Auxiliary β1 Subunit
por: He, Bingjun, et al.
Publicado: (2014)

The opioid tramadol blocks the cardiac sodium channel Na(v)1.5 in HEK293 cells
por: Jia, Lixia, et al.
Publicado: (2023)

Production, purification and characterization of recombinant human R-spondin1 (RSPO1) protein stably expressed in human HEK293 cells
por: Levin, Gabriel, et al.
Publicado: (2020)

Lack of current observed in HEK293 cells expressing NALCN channels
por: Egan, Jennifer M., et al.
Publicado: (2018)

Na(+)/Ca(2+) selectivity in the bacterial voltage-gated sodium channel NavAb
por: Corry, Ben
Publicado: (2013)

Effect of trans-sodium crocetinate on contrast-induced cytotoxicity in HEK-293 cells
por: Rajabian, Fatemeh, et al.
Publicado: (2023)

β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Na(v)1.7 in HEK293 cells
por: Laedermann, Cédric J., et al.
Publicado: (2013)

Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics
por: Dvorak, Nolan M., et al.
Publicado: (2020)

The Functional Role of Voltage-Gated Sodium Channel Nav1.5 in Metastatic Breast Cancer
por: Luo, Qianxuan, et al.
Publicado: (2020)

Role of the voltage-gated sodium channel Nav1.6 in glioma and candidate drugs screening
por: Ai, Yong, et al.
Publicado: (2023)

Allitridi Inhibits Multiple Cardiac Potassium Channels Expressed in HEK 293 Cells
por: Xu, Xiao-Hui, et al.
Publicado: (2012)

Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity
por: Kerth, Clara M., et al.
Publicado: (2020)

Voltage sensor dynamics of a bacterial voltage-gated sodium channel NavAb reveal three conformational states
por: Han, Shuo, et al.
Publicado: (2023)

Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells
por: Yu, Dahai, et al.
Publicado: (2017)

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABA(A) Receptors
por: Brown, Laura E., et al.
Publicado: (2014)

Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na (v)1.5 expressed in HEK293 cells
por: Reinhard, Katja, et al.
Publicado: (2013)

Identification of Navβ1 Residues Involved in the Modulation of the Sodium Channel Nav1.4
por: Islas, Angel A., et al.
Publicado: (2013)

Regulation of Kv4.2 A-Type Potassium Channels in HEK-293 Cells by Hypoxia
por: Liu, Yu-Qiang, et al.
Publicado: (2014)

Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation
por: Tricarico, Domenico, et al.
Publicado: (2013)

HEK293S Cells Have Functional Retinoid Processing Machinery
por: Brueggemann, Lioubov I., et al.
Publicado: (2002)

Effects of endotoxin on pacemaker funny current in HEK 293 cells
por: Papaioannou, VP, et al.
Publicado: (2011)

Echinacea-induced cytosolic Ca(2+ )elevation in HEK293
por: Wu, Lankun, et al.
Publicado: (2010)

Effect of PTTG on endogenous gene expression in HEK 293 cells
por: Panguluri, Siva K, et al.
Publicado: (2009)

Analysis of DNA topology of EBV minichromosomes in HEK 293 cells
por: Castán, Alicia, et al.
Publicado: (2017)

HEK293T cell lines defective for O-linked glycosylation
por: Termini, James M., et al.
Publicado: (2017)

Microtubule Integrity Is Associated with the Functional Activity of Mitochondria in HEK293
por: Cho, Min Jeong, et al.
Publicado: (2021)

Deconstructing voltage sensor function and pharmacology in sodium channels
por: Bosmans, Frank, et al.
Publicado: (2008)

Cytosolic domain regulates the calcium sensitivity and surface expression of BEST1 channels in the HEK293 cells
por: Kim, Kwon Woo, et al.
Publicado: (2023)

Noxious chemical discrimination by Tribolium castaneum TRPA1 channel in the HEK293 cell expression system()()
por: Shimomura, Kenji, et al.
Publicado: (2023)

Syringin inhibits endogenous volume regulated anion channel currents of HEK293 cells in hypotonic circumstances
por: Xu, Ziwei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c97ir73m4gg5lgditunin091q4