Association of Fidaxomicin with C. difficile Spores: Effects of Persistence on Subsequent Spore Recovery, Outgrowth and Toxin Production

BACKGROUND: We have previously shown that fidaxomicin instillation prevents spore recovery in an in-vitro gut model, whereas vancomycin does not. The reasons for this are unclear. Here, we have investigated persistence of fidaxomicin and vancomycin on C. difficile spores, and examined post-antibioti...

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Detalles Bibliográficos
Autores principales: Chilton, Caroline H., Crowther, Grace S., Ashwin, Helen, Longshaw, Chris M., Wilcox, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996525/
https://www.ncbi.nlm.nih.gov/pubmed/27556739
http://dx.doi.org/10.1371/journal.pone.0161200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996525/
https://www.ncbi.nlm.nih.gov/pubmed/27556739
http://dx.doi.org/10.1371/journal.pone.0161200

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