Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1

During placental malaria, Plasmodium falciparum infected erythrocytes sequester in the placenta, causing health problems for both the mother and fetus. The specific adherence is mediated by the VAR2CSA protein, which binds to placental chondroitin sulfate (CS) on chondroitin sulfate proteoglycans (C...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayres Pereira, Marina, Mandel Clausen, Thomas, Pehrson, Caroline, Mao, Yang, Resende, Mafalda, Daugaard, Mads, Riis Kristensen, Anders, Spliid, Charlotte, Mathiesen, Line, E. Knudsen, Lisbeth, Damm, Peter, G. Theander, Thor, R. Hansson, Stefan, A. Nielsen, Morten, Salanti, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996535/
https://www.ncbi.nlm.nih.gov/pubmed/27556547
http://dx.doi.org/10.1371/journal.ppat.1005831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996535/
https://www.ncbi.nlm.nih.gov/pubmed/27556547
http://dx.doi.org/10.1371/journal.ppat.1005831

Ejemplares similares