Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis

A patient with history of a solitary functioning kidney and protein C deficiency (PCD) presented with recurrent severe hydronephrosis causing acute kidney injury upon chronic kidney disease. Work-up with endoscopic evaluation revealed renal papillary necrosis (RPN) and sloughed renal papillae to be...

Descripción completa

Detalles Bibliográficos
Autores principales: Chugh, Rohit Kumar, Olorunnisomo, Vincent, Fowle, Evan James, Modica, Ippolito, Meisels, Ira, Gupta, Mantu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996589/
https://www.ncbi.nlm.nih.gov/pubmed/27579411
http://dx.doi.org/10.1089/cren.2016.0018
_version_ 1782449632443367424
author Chugh, Rohit Kumar
Olorunnisomo, Vincent
Fowle, Evan James
Modica, Ippolito
Meisels, Ira
Gupta, Mantu
author_facet Chugh, Rohit Kumar
Olorunnisomo, Vincent
Fowle, Evan James
Modica, Ippolito
Meisels, Ira
Gupta, Mantu
author_sort Chugh, Rohit Kumar
collection PubMed
description A patient with history of a solitary functioning kidney and protein C deficiency (PCD) presented with recurrent severe hydronephrosis causing acute kidney injury upon chronic kidney disease. Work-up with endoscopic evaluation revealed renal papillary necrosis (RPN) and sloughed renal papillae to be the true cause of the recurrent obstruction. Pathologic evaluation of the sloughed tissue confirmed the diagnosis of RPN. This is the first case reported in the literature illustrating the unique presentation of RPN in the setting of PCD.
format Online
Article
Text
id pubmed-4996589
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Mary Ann Liebert, Inc.
record_format MEDLINE/PubMed
spelling pubmed-49965892016-08-30 Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis Chugh, Rohit Kumar Olorunnisomo, Vincent Fowle, Evan James Modica, Ippolito Meisels, Ira Gupta, Mantu J Endourol Case Rep Case Report A patient with history of a solitary functioning kidney and protein C deficiency (PCD) presented with recurrent severe hydronephrosis causing acute kidney injury upon chronic kidney disease. Work-up with endoscopic evaluation revealed renal papillary necrosis (RPN) and sloughed renal papillae to be the true cause of the recurrent obstruction. Pathologic evaluation of the sloughed tissue confirmed the diagnosis of RPN. This is the first case reported in the literature illustrating the unique presentation of RPN in the setting of PCD. Mary Ann Liebert, Inc. 2016-02-01 /pmc/articles/PMC4996589/ /pubmed/27579411 http://dx.doi.org/10.1089/cren.2016.0018 Text en © Rohit Kumar Chugh et al. 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Case Report
Chugh, Rohit Kumar
Olorunnisomo, Vincent
Fowle, Evan James
Modica, Ippolito
Meisels, Ira
Gupta, Mantu
Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis
title Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis
title_full Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis
title_fullStr Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis
title_full_unstemmed Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis
title_short Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis
title_sort renal papillary necrosis caused by protein c deficiency leading to recurrent hydronephrosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996589/
https://www.ncbi.nlm.nih.gov/pubmed/27579411
http://dx.doi.org/10.1089/cren.2016.0018
work_keys_str_mv AT chughrohitkumar renalpapillarynecrosiscausedbyproteincdeficiencyleadingtorecurrenthydronephrosis
AT olorunnisomovincent renalpapillarynecrosiscausedbyproteincdeficiencyleadingtorecurrenthydronephrosis
AT fowleevanjames renalpapillarynecrosiscausedbyproteincdeficiencyleadingtorecurrenthydronephrosis
AT modicaippolito renalpapillarynecrosiscausedbyproteincdeficiencyleadingtorecurrenthydronephrosis
AT meiselsira renalpapillarynecrosiscausedbyproteincdeficiencyleadingtorecurrenthydronephrosis
AT guptamantu renalpapillarynecrosiscausedbyproteincdeficiencyleadingtorecurrenthydronephrosis

Ejemplares similares