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A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices

Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressiv...

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Autores principales: Kelly, Deirdre, Mc Erlean, Sarah, Byrne, Danielle, Mahon, Peter Mac, Mc Caffrey, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996899/
https://www.ncbi.nlm.nih.gov/pubmed/27594954
http://dx.doi.org/10.1016/j.radcr.2016.04.009
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author Kelly, Deirdre
Mc Erlean, Sarah
Byrne, Danielle
Mahon, Peter Mac
Mc Caffrey, John
author_facet Kelly, Deirdre
Mc Erlean, Sarah
Byrne, Danielle
Mahon, Peter Mac
Mc Caffrey, John
author_sort Kelly, Deirdre
collection PubMed
description Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting.
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spelling pubmed-49968992016-09-02 A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices Kelly, Deirdre Mc Erlean, Sarah Byrne, Danielle Mahon, Peter Mac Mc Caffrey, John Radiol Case Rep Case Report Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting. Elsevier 2016-05-25 /pmc/articles/PMC4996899/ /pubmed/27594954 http://dx.doi.org/10.1016/j.radcr.2016.04.009 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kelly, Deirdre
Mc Erlean, Sarah
Byrne, Danielle
Mahon, Peter Mac
Mc Caffrey, John
A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
title A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
title_full A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
title_fullStr A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
title_full_unstemmed A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
title_short A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
title_sort case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996899/
https://www.ncbi.nlm.nih.gov/pubmed/27594954
http://dx.doi.org/10.1016/j.radcr.2016.04.009
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