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A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressiv...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996899/ https://www.ncbi.nlm.nih.gov/pubmed/27594954 http://dx.doi.org/10.1016/j.radcr.2016.04.009 |
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author | Kelly, Deirdre Mc Erlean, Sarah Byrne, Danielle Mahon, Peter Mac Mc Caffrey, John |
author_facet | Kelly, Deirdre Mc Erlean, Sarah Byrne, Danielle Mahon, Peter Mac Mc Caffrey, John |
author_sort | Kelly, Deirdre |
collection | PubMed |
description | Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting. |
format | Online Article Text |
id | pubmed-4996899 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49968992016-09-02 A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices Kelly, Deirdre Mc Erlean, Sarah Byrne, Danielle Mahon, Peter Mac Mc Caffrey, John Radiol Case Rep Case Report Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting. Elsevier 2016-05-25 /pmc/articles/PMC4996899/ /pubmed/27594954 http://dx.doi.org/10.1016/j.radcr.2016.04.009 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Kelly, Deirdre Mc Erlean, Sarah Byrne, Danielle Mahon, Peter Mac Mc Caffrey, John A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
title | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
title_full | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
title_fullStr | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
title_full_unstemmed | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
title_short | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
title_sort | case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996899/ https://www.ncbi.nlm.nih.gov/pubmed/27594954 http://dx.doi.org/10.1016/j.radcr.2016.04.009 |
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