A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes

Ubiquitin (Ub) is a protein modifier that controls processes ranging from protein degradation to endocytosis, but early-acting regulators of the three-enzyme ubiquitylation cascade are unknown. Here we report that the prenylated membrane-anchored ubiquitin-fold protein (MUB) is an early-acting regul...

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Detalles Bibliográficos
Autores principales: Lu, Xiaolong, Malley, Konstantin R., Brenner, Caitlin C., Koroleva, Olga, Korolev, Sergey, Downes, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996978/
https://www.ncbi.nlm.nih.gov/pubmed/27550514
http://dx.doi.org/10.1038/ncomms12580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996978/
https://www.ncbi.nlm.nih.gov/pubmed/27550514
http://dx.doi.org/10.1038/ncomms12580

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