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Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital

Background. Neonatal deaths constitute the majority of child mortality in Vietnam, but studies are scarce and focus on community settings. Methods. During a 12-month period, all sick neonates admitted to a pediatric department in a province hospital were studied. Potential risk factors of death cove...

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Autores principales: Ho, Binh T. T., Kruse, Alexandra Y., Le, Hue T. H., Cam, Phuong N., Pedersen, Freddy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997011/
https://www.ncbi.nlm.nih.gov/pubmed/27597956
http://dx.doi.org/10.1155/2016/2087042
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author Ho, Binh T. T.
Kruse, Alexandra Y.
Le, Hue T. H.
Cam, Phuong N.
Pedersen, Freddy K.
author_facet Ho, Binh T. T.
Kruse, Alexandra Y.
Le, Hue T. H.
Cam, Phuong N.
Pedersen, Freddy K.
author_sort Ho, Binh T. T.
collection PubMed
description Background. Neonatal deaths constitute the majority of child mortality in Vietnam, but studies are scarce and focus on community settings. Methods. During a 12-month period, all sick neonates admitted to a pediatric department in a province hospital were studied. Potential risk factors of death covering sociodemographic factors, pregnancy history, previous neonatal period, and status on admission were registered. The neonates were followed up until discharge or death or until 28 completed days of age if still hospitalized or until withdrawal of life support. The main outcome was neonatal death. Results. The neonatal mortality was 4.6% (50/1094). In a multivariate analysis, four associated risk factors of death were extremely low birth weight (OR = 22.9 (2.3–233.4)), no cry at birth (OR = 3.5 (1.3–9.4)), and cyanosis (OR = 3.3 (1.2–8.7)) and shock (OR = 12.3 (2.5–61.5)) on admission. The major discharge diagnoses were infection, prematurity, congenital malformations, and asphyxia in 88.5% (936/1058), 21.3% (225/1058), 5.0% (53/1058), and 4.6% (49/1058), respectively. In 36, a discharge diagnosis was not registered. Conclusion. Infection was the main cause of neonatal morbidity. Asphyxia and congenital malformations were diagnosed less frequently. The neonatal mortality was 4.6%. No sociodemographic factors were associated with death. Extreme low birth weight, no cry at birth, and cyanosis or shock at admission were associated with death.
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spelling pubmed-49970112016-09-05 Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital Ho, Binh T. T. Kruse, Alexandra Y. Le, Hue T. H. Cam, Phuong N. Pedersen, Freddy K. Biomed Res Int Research Article Background. Neonatal deaths constitute the majority of child mortality in Vietnam, but studies are scarce and focus on community settings. Methods. During a 12-month period, all sick neonates admitted to a pediatric department in a province hospital were studied. Potential risk factors of death covering sociodemographic factors, pregnancy history, previous neonatal period, and status on admission were registered. The neonates were followed up until discharge or death or until 28 completed days of age if still hospitalized or until withdrawal of life support. The main outcome was neonatal death. Results. The neonatal mortality was 4.6% (50/1094). In a multivariate analysis, four associated risk factors of death were extremely low birth weight (OR = 22.9 (2.3–233.4)), no cry at birth (OR = 3.5 (1.3–9.4)), and cyanosis (OR = 3.3 (1.2–8.7)) and shock (OR = 12.3 (2.5–61.5)) on admission. The major discharge diagnoses were infection, prematurity, congenital malformations, and asphyxia in 88.5% (936/1058), 21.3% (225/1058), 5.0% (53/1058), and 4.6% (49/1058), respectively. In 36, a discharge diagnosis was not registered. Conclusion. Infection was the main cause of neonatal morbidity. Asphyxia and congenital malformations were diagnosed less frequently. The neonatal mortality was 4.6%. No sociodemographic factors were associated with death. Extreme low birth weight, no cry at birth, and cyanosis or shock at admission were associated with death. Hindawi Publishing Corporation 2016 2016-08-11 /pmc/articles/PMC4997011/ /pubmed/27597956 http://dx.doi.org/10.1155/2016/2087042 Text en Copyright © 2016 Binh T. T. Ho et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ho, Binh T. T.
Kruse, Alexandra Y.
Le, Hue T. H.
Cam, Phuong N.
Pedersen, Freddy K.
Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital
title Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital
title_full Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital
title_fullStr Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital
title_full_unstemmed Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital
title_short Low Neonatal Mortality and High Incidence of Infectious Diseases in a Vietnamese Province Hospital
title_sort low neonatal mortality and high incidence of infectious diseases in a vietnamese province hospital
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997011/
https://www.ncbi.nlm.nih.gov/pubmed/27597956
http://dx.doi.org/10.1155/2016/2087042
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