Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1/2/5 Pathway

Patent ductus arteriosus (PDA) can cause morbidity and mortality in neonates. Vascular remodeling, characterized by proliferation and migration of smooth muscle cells (SMCs), is an essential process for postnatal DA closure. Notch signaling is an important mediator of vascular remodelling but its ro...

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Detalles Bibliográficos
Autores principales: Wu, Jiunn-Ren, Yeh, Jwu-Lai, Liou, Shu-Fen, Dai, Zen-Kong, Wu, Bin-Nan, Hsu, Jong-Hau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997050/
https://www.ncbi.nlm.nih.gov/pubmed/27570480
http://dx.doi.org/10.7150/ijbs.16430

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