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Analysis of PBase Binding Profile Indicates an Insertion Target Selection Mechanism Dependent on TTAA, But Not Transcriptional Activity

Transposons and retroviruses are important pathogenic agents and tools for mutagenesis and transgenesis. Insertion target selection is a key feature for a given transposon or retrovirus. The piggyBac (PB) transposon is highly active in mice and human cells, which has a much better genome-wide distri...

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Detalles Bibliográficos
Autores principales:	Yang, Dong, Liao, Ruiqi, Zheng, Yun, Sun, Ling, Xu, Tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997051/ https://www.ncbi.nlm.nih.gov/pubmed/27570481 http://dx.doi.org/10.7150/ijbs.15589

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