Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion

Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration and disease treatment. However, long-term in vitro passaging leads to stemness loss of MSCs, resulting in failure of MSCs therapy. Here, we report a melatonin-based strategy to improve cell therapy of in vitro cultured MS...

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Detalles Bibliográficos
Autores principales: Shuai, Yi, Liao, Li, Su, Xiaoxia, Yu, Yang, Shao, Bingyi, Jing, Huan, Zhang, Xinjing, Deng, Zhihong, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997245/
https://www.ncbi.nlm.nih.gov/pubmed/27570559
http://dx.doi.org/10.7150/thno.15412

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