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AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-κB and STAT3 Pathways

Renin angiotensin system (RAS) is a key hormonal system which regulates the cardiovascular function and is implicated in several autoimmune diseases. With the discovery of the angiotensin-converting enzyme 2 (ACE2), a protective axis of RAS namely ACE2/Ang-(1–7)/Mas that counteracts the deleterious...

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Detalles Bibliográficos
Autores principales:	Qiu, Yiguo, Tao, Lifei, Zheng, Shijie, Lin, Ru, Fu, Xinyu, Chen, Zihe, Lei, Chunyan, Wang, Jiaming, Li, Hongwei, Li, Qiuhong, Lei, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997264/ https://www.ncbi.nlm.nih.gov/pubmed/27558087 http://dx.doi.org/10.1038/srep31912

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