Detection of nucleotide-specific CRISPR/Cas9 modified alleles using multiplex ligation detection

CRISPR/Cas9 genome-editing has emerged as a powerful tool to create mutant alleles in model organisms. However, the precision with which these mutations are created has introduced a new set of complications for genotyping and colony management. Traditional gene-targeting approaches in many experimen...

Descripción completa

Detalles Bibliográficos
Autores principales: KC, R., Srivastava, A., Wilkowski, J. M., Richter, C. E., Shavit, J. A., Burke, D. T., Bielas, S. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997339/
https://www.ncbi.nlm.nih.gov/pubmed/27557703
http://dx.doi.org/10.1038/srep32048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997339/
https://www.ncbi.nlm.nih.gov/pubmed/27557703
http://dx.doi.org/10.1038/srep32048

Ejemplares similares