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Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model
Several lines of evidence suggest that neuregulin 1 (NRG1) signaling may influence cognitive function and neuropathology in Alzheimer’s disease (AD). To test this possibility, full-length type I or type III NRG1 was overexpressed via lentiviral vectors in the hippocampus of line 41 AD mouse. Both ty...
Autores principales: | Xu, Jiqing, de Winter, Fred, Farrokhi, Catherine, Rockenstein, Edward, Mante, Michael, Adame, Anthony, Cook, Jonathan, Jin, Xin, Masliah, Eliezer, Lee, Kuo-Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997345/ https://www.ncbi.nlm.nih.gov/pubmed/27558862 http://dx.doi.org/10.1038/srep31692 |
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