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Exactin: A specific inhibitor of Factor X activation by extrinsic tenase complex from the venom of Hemachatus haemachatus

Unwanted clots lead to heart attack and stroke that result in a large number of deaths. Currently available anticoagulants have some drawbacks including their non-specific actions. Therefore novel anticoagulants that target specific steps in the coagulation pathway are being sought. Here we describe...

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Detalles Bibliográficos
Autores principales: Girish, Vallerinteavide Mavelli, Kini, R. Manjunatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997346/
https://www.ncbi.nlm.nih.gov/pubmed/27558950
http://dx.doi.org/10.1038/srep32036